Exciting scientific research on marijuana finally emerging
There is an old joke which sums up the rivalry between Ireland’s top two universities. In UCD when the lecturer says good morning to the class, they say good morning back. When a lecturer walks into a class at Trinity University ands says good morning, the students write good morning down. Well it looks like Trinity is having the last laugh now, as two of its researchers, Veronica Campbell and Steve Fagen have linked the active ingredient in marijuana, THC with its ability to keep the brain younger. It seems that the anti-inflammatory properties of THC as well as its role in regulating cell behavior are key to the well being of older brains. Parkinson’s disease, Alzheimer’s and a whole host of other brain degenerative diseases will have treatments based on marijuana compounds. The science is exciting, and the next step forward in anti aging has taken place.
A pot smoker doesn’t harm anyone, but the politician and power hungry officials that are blocking research on cannabis are. In a fair world, which one of these two people actually deserves to go to prison?
Below is the science from Campbell’s and Fagen’s research, it is heavy and technical, but it is also ground breaking so I wanted to include it, enjoy!
In an increasingly ageing population, the incidence of neurodegenerative disorders such as Alzheimer’s disease, Parkinson’s disease and Huntington’s disease are rising. While the aetiologies of these disorders are different, a number of common mechanisms that underlie their neurodegenerative components have been elucidated; namely neuroinflammation, excitotoxicity, mitochondrial dysfunction and reduced trophic support. Current therapies focus on treatment of the symptoms and attempt to delay the progression of these diseases but there is currently no cure. Modulation of the endogenous cannabinoid system is emerging as a potentially viable option in the treatment of neurodegeneration. Endocannabinoid signalling has been found to be altered in many neurodegenerative disorders. To this end, pharmacological manipulation of the endogenous cannabinoid system, as well as application of phytocannabinoids and synthetic cannabinoids have been investigated. Signalling from the CB1 and CB2 receptors are known to be involved in the regulation of Ca(2+) homeostasis, mitochondrial function, trophic support and inflammatory status, respectively, while other receptors gated by cannabinoids such as PPARγ, are gaining interest in their anti-inflammatory properties. Through multiple lines of evidence, this evolutionarily conserved neurosignalling system has shown neuroprotective capabilities and is therefore a potential target for neurodegenerative disorders.